University of Hawaii at Manoa | Department of Microbiology

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Gideon Berger Gideon Berger
Department of Chemistry
University of Hawaii
2545 McCarthy Mall
Honolulu, HI 96822
(530) 220-7684 (phone)
gidberg@hotmail.com

Education

Postdoctoral: Natural Product Total Synthesis; Synthetic Methodology. Marcus A. Tius, Advisor.		University of Hawaii at Manoa
Ph.D. Synthetic Organic Chemistry: “Liposome Polymerization and Applications Using Novel Aminooxy and Carbonyl Lipids”. Michael H. Nantz, Advisor.	2004	University of California, Davis
B.A. Chemistry	1999	California State University, Sacramento
B.A. Psychology	1993	University of California, Davis

Research Summary

My expertise lies in synthetic organic chemistry. Specifically, I have specialized in natural products total synthesis. Natural products total synthesis is the reconstruction of complex targets found in nature, conducted in the laboratory from simple commercially available materials. This is undertaken for many reasons but two of the main reasons are to address scarcity problems and to develop new elegant ways of assembling complex carbon frameworks.

Selected Publications

G.O. Berger & M.A. Tius. 2007. Total Synthesis of (±)-Terpestacin and (±)-epi-Terpestacin. J. Org. Chem. 72: 6473-6480.

J.G. Hecker, G.O. Berger, K.A. Scarfo, & M.H. Nantz. A Simple, Flexible Method for the Conjugation of Aminooxy Ligands to Pre-Formed Lipoplexes. Molecular Therapy. In preparation.

G.O. Berger & M.A. Tius. 2005. Terpestacin Core Structure. Control of Stereochemistry. Org Lett. 7: 5011-5013.

A. R. Banaag, G. O. Berger, F. Dhoro, D. B. delos Santos, D. D. Dixon, J. P. Mitchel, B. K. Bradley, M. A. Tius. 2005. Tandem alkylation-cyclization process via an O,C-dianion. Tetrahedron. 61: 3419-3428.

M.F. Springsteel, L. J.V. Galietta, T. Ma, K. By, G.O. Berger, H. Yang, C.W. Dicus, W. Choung, C. Quan, A.A. Shelat, R.K. Guy, A.S. Verkman, M.J. Kurth, & M.H. Nantz. 2003. Benzoflavone Activators of the Cystic Fibrosis Transmembrane Conductance Regulator: A Pharmacophore Model for the -Binding Domain. Bioorg. Med. Chem. 11: 4113-4120.

P.A. Kelly, G.O. Berger, J.K. Wyatt, & M.H. Nantz. 2003. Synthesis of [Ethylene-1-(h5-4, 5, 6, 7-tetrahydro-1-indenyl)-2-(h5-4', 5', 6', 7'-tetrahydro-2'-indenyl)]titanium Dichloride, the Elusive Isomer of the Brintzinger-Type ansa-Titanocenes. Journal of Organic Chemistry. 68: 8447-8452.