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Using Magnetic Resonance Techniques to Study the Brain and Brain Diseases |
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Principal Investigator |
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EDUCATION B.S. Biology, Univ. of California at Irvine B.A. Psychology, Univ. of California at Irvine, June 1993 Ph.D. Neuroscience, Univ. of California at Los Angeles, March 2002 ACADEMIC HONORS 1988 Regents Honors award upon entrance to University of California, Irvine Psi Chi psychology honors nomination for research in Honors Experimental Psychology at UC Irvine 1992-1993 Sigma Xi science honors nominations for research in psychology and biology at UC Irvine 1993 Excellence in Undergraduate Research in Biology at University of California, Irvine. 1993 Campus-wide Honors Program completion at University of California, Irvine PROFESSIONAL EXPERIENCES 1990-1994 Part-time volunteer research in the laboratory of John F. Marshall Ph.D. Department of Psychobiology, University of California, Irvine. Part time graduate laboratory rotation in the lab of William P. Melega Ph.D., Department of Pharmachology UCLA. 1996-2002 Graduate research in the lab of Russell E. Poland Ph.D. Interdepartmental Neuroscience Program UCLA 1997-2000 Full time: Research Student Fellow, Harbor-UCLA Medical Center, Torrance CA 2000-2002 Full time: Research Student Fellow, Cedars-Sinai Medical Center, Los Angeles, CA Part-time: Teaching Assistant to Dr Arnold Scheibel, UCLA Functional Neuroanatomy 102 1999-2002 Part-time volunteer: Project Brainstorm, Interdepartmental Neuroscience Program UCLA [visit local schools (grades 3-12) to teach age appropriate neuroscience and “how to take care of your brain”] 2002 - 2004 NIDA T-32 Post-Doctoral Fellow, Medical Department Brookhaven National Laboratory, Upton, NY 2004-present Assistant Professor, John A Burns School of Medicine, Department of Medicine, University of Hawaii, Honolulu HI CURRENT SOCIETY MEMBERSHIPS 1998-present Member, Society for Neuroscience 1999-present Member, International Society of Magnetic Resonance in Medicine 2003-2004 Member, International Society on NeuroVirology HONORS / AWARDS 1999, 2000 & 2002 ISMRM Student Stipend Travel Award 2002, 2004 SNIP Young Investigator Award 2003 CPDD Junior Investigator Travel Award 2003 ISNV Investigator in Training Travel Award PEER-REVIWED PUBLICATION PAPERS Cloak CC, Marshall JF: Effects of acute haloperidol and clozapine treatments on MK-801 and d-amphetamine induced behaviors. Journal of Undergraduate Research in the Biological Sciences University of California, Irvine. 23:453-464,1993. Poland RE, Cloak CC, Lutchmansingh PJ, McCracken JT, Chang L, Ernst T: Brain N-acetyl aspartate concentrations measured by 1H MRS are reduced in adult male rats subjected to perinatal stress: preliminary observations and hypothetical implications for neurodevelopmental disorders. Journal of Psychiatry Research, 33:N1:41-51 1999. Poland RE, Pechnick RN, Cloak CC, Wan YY, Nuccio I, Lin, KM. Effect of cigarette smoking on coumarin metabolism in humans. Nicotine and Tobacco Research 2(4) 351-4, 2001. Smith LM, Cloak CC, Poland RE, Torday J, Ross MG. Prenatal nicotine increases testosterone levels in the fetus and female offspring. Nicotine and Tobacco Research 5(3):369-74, 2003. Cloak CC, Chang L, Ernst T, Phillips T, Huitron-Resendiz S, Sanchez-Alavez M, Hampton V, Henriksen S. Methamphetamine and AIDS: ex vivo 1HMRS in a Feline Model. Journal of NeuroImmunology 147:16–20, 2004. Cloak CC, Chang L, Ernst T. Increased Frontal White Matter Diffusion is Associated with Glial Metabolites and Psychomotor Slowing in HIV. Journal of NeuroImmunology . 2004 Dec;157(1-2):147-52. Chang L, Cloak CC, Patterson K, Grob C, Miller EN, and Ernst T. Enlarged Striatum in Abstinent Methamphetamine Abusers: a Possible Compensatory Response. Biological Psychiatry. 2005 May 1;57(9):967-74. Chang SL, Cloak CC, Malellari L, Chang L, The Effects of Repeated Endotoxin Exposure on Rat Metabolites as Measured by ex vivo 1HMRS. Journal of Neuroimmunology. 2005 Sep 166(1-2):39-46. Cloak CC, Poland RE. Variations in Brain Chemistry Detected by Proton MRS between Normal Males and Females. NMR in Biomed (in revision). Chang L, Cloak C, Yakupov R, Ernst T, Marijuana use is associated with a reorganized visual attention network and cerebellar hypoactivity. Brain (in revision). Chang L, Cloak C, Yakupov R, Ernst T, Interaction between chronic marijuana use and HIV on brain glutamate. Journal of Neuroimmune Pharmacology. (submitted). Chang L, Wong V, Nakama H, Watters M, Ramones D, Miller EN, Cloak C, Ernst T. Greater Than Age-Related Changes in Brain Diffusion of HIV Patients After 1 Year. Journal of Neuroimmune Pharmacology. 3(4):265-74, 2008 Nakama H, Chang L, Cloak C, Jiang C, Alicata D, Haning W, Association between psychiatric symptoms and craving in methamphetamine users. American Journal on Addictions 17(5):441-6, 2008 Cloak C, Ernst T, Fujii L, Hedemark B, Chang L. Lower Diffusion in White Matter of Children with Prenatal Methamphetamine Exposure. Neurology (in press) Abstracts and Presentations Cloak CC, Poland RE. Long-term Neurotoxic Effects of In Utero Nicotine Exposure as Detected by 1H MRS. Proceedings of the Society For Neuroscience, Abstract 751 (SFN 28th Annual Meeting, Los Angeles, CA, 1998). Cloak CC, Chang L, Ernst T, Smith L, Poland RE. Long-Term Effects of In Utero Nicotine or Cocaine Exposure as Detected by Ex Vivo 1H MRS. Proceedings of the International Society for Magnetic Resonance in Medicine Abstract 1480. (ISMRM, 7th Annual Meeting, Philadelphia, PA, 1999). Cloak CC, Lutchmansingh P, Poland RE. Neurotoxic Effects of MDMA as Detected by 1H MRS. CPDD Abstract. 7:24, (College of Problems in Drug Dependence, 61st Annual Scientific Meeting. (Acapulco, Mexico, 1999). Cloak CC, Chang L, Ernst T, Poland RE. Postmortem Stability of 1H MRS Metabolites in Rat Brain. Proceedings of the International Society for Magnetic Resonance in Medicine; Abstract 1074. (ISMRM, 8th Annual Meeting, Denver, CO, April 1-7, 2000). Cloak CC, Poland RE. Effects of Peripuberal Nicotine Exposure on the Brain as detected by 1H MRS. Proceedings of the Society For Neuroscience, Abstract (SFN 30th Annual Meeting, New Orleans, LA, 2000). Cloak CC, Poland RE. Hemispheric and Gender Differences in Brain Metabolites in Normal Rat Brain Detected by 1H MRS. Proceedings of the International Society for Magnetic Resonance in Medicine Abstract 589, (Talk ISMRM, 10th Annual Meeting Honolulu, HI 2002). Cloak CC, Poland RE. Long-Term Effects of In Utero Nicotine Exposure on Striatal GABA as Measured by Ex Vivo 1H MRS. Abstract 962, (Poster ISMRM, 10th Annual Meeting Honolulu, HI 2002). Cloak CC, Poland RE. Combined Prenatal and Peripuberal Nicotine Exposure Assessed by 1H MRS. Abstract, (Young Investigator Poster P31 SNIP Annual Meeting Clearwater, FL 2002). CC Cloak, L Chang, T Ernst, T Phillips, S Huitron-Resendiz, M Sanchez-Alavez, V Hampton, S Henriksen. Methamphetamine and AIDS: ex vivo 1HMRS in a Feline Model Abstract submitted (ISMRM 2003) Cloak CC, Chang L, Patterson K, Grob C, Miller EN, and Ernst T: Sex-Differences in Neuropsychological Function and Brain Morphometry in Methamphetamine Users. College of Problems in Drug Dependence, 65th Annual Scientific Meeting. (Talk and travel award CPDD, Bal Harbor, FL, 2003) Cloak CC, Chang L, Miller EN, Ernst T. Poorer cognitive scores in HIV are associated with increased white matter diffusion. (Talk and travel award ISNV Baltimore MD, 2003). Cloak CC, Chang L, Conant K, Ernst T; Zimmerman L; Miller EN. Increased CSF Monocyte Chemotactic Protein1 Correlates with Psychomotor Slowing in HIV Patients. Proceedings of the Society For Neuroscience, (Poster: SFN 33th Annual Meeting, New Orleans, LA, 2003). Cloak CC, Chang L, Passman J, Chang SL. Chronic Endotoxin Exposure Decreases Choline and Increases Lactate as Measured by Ex Vivo 1HMRS (Poster for ISMRM, 2004) Chang L, Leckova K, Cloak C, Arnold S, Yakupov R, Lozar C, Warren K, Ernst T. Decreased BOLD Activation during Visual Attention Tasks in Marijuana Abusers. (Talk for ISMRM, 2004) C Cloak, L Chang, K Leckova, K Warren, T Ernst. Brain Chemistry Altered by HIV & Marijuana (Poster SNIP, 2004) K Leckova, L Chang, C Cloak, K Warren, E Miller. Marijuana Exacerbates Psychomotor Slowing in HIV (Poster SNIP, 2004) L Chang, D Tomasi, K Leckova, K Warren, E Caparelli, R Yakupov, C Lozar, C Cloak, T Ernst. Marijuana and Aging on Attention in HIV (Poster SNIP, 2004) K Warren, C Cloak, K Leckova, L Chang. HIV Infection and Marijuana Use Have Additive Effects on Psychological Symptoms (Poster SNIP, 2004) Review Articles: Chang L, Cloak CC, Ernst T. Magnetic Resonance Spectroscopy Studies of GABA in Neuropsychiatric Disorders. Journal of Clinical Psychiatry 64 (Supl 3) 7-14, 2003.
Home | Publications | Investigators | Postdoctoral Researchers | Students | Staff | Usage of the 3T Scanner | Volunteers | Related Links | Calendar Neuroscience and MR Research Program, Department of Medicine—JABSOM, University of Hawaii, 1356 Lusitana Street, 7th Floor, Honolulu, HI 96813 Carol Kosaki: 808-545-8968; Linda Cunningham: 808-545-8973; Fax: 808-545-8970; Email: nmr@hawaii.edu Last update: January 2009. |
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Christine Cloak, Ph.D. Assistant Professor |
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CURRICULUM VITAE: |
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Department of Medicine, John A. Burns School of Medicine, University of Hawai'i, 1356 Lusitana Street, University Tower, 7th Floor, Honolulu, HI 96813 |
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Email: cloak@hawaii.edu Phone: 808-586-7459 Fax: 808-586-7486 |
