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Ongoing Research Support

  • A COBRE Center for Cardiovascular Research
    NIH/NCCR
    To support infrastructure and career development for promising young investigators in cardiovascular disciplines at the University of Hawaii.
    Abstract

  • Research in Molecular Cardiology
    NIH/NHLBI
    To establish a molecular cardiology laboratory and program at the John A. Burns School of Medicine to enhance opportunities for cardiology research at the University of Hawaii.
    Abstract

  • Transcriptional and Physiological Analysis of Cardiac HIF-1
    NIH 1-RO-1
    To define the role of HIF-1 within the heart.
    Abstract

  • Transcriptional Analysis of Pollutant Exposure
    NIH/NIEHS 1-RO-1
    To define the vascular endothelial response to diesel exhaust.
    Abstract

Recently Concluded Research Support

  • Genetic Analysis of Signaling by Cardiac Endothelin-1
    NIH/NHLBI 1-RO-1
    To elucidate the role of cardiomyocyte ET-1 in models of cardiac hypertrophy.

  • Genetic epidemiology of atherosclerosis and heart failure
    Leducq Foundation Award (Co-PI with J Cohen)
    To investigate the genetic basis of atherosclerosis and heart failure.

  • Genomics and proteomics of cell injury and inflammation
    NIH/NHLBI (PI: S Johnston)
    To create and apply microarray resources to identify transcriptionally regulated candidate genes for subsequent genetic analysis.

  • Application of ultrasound targeted microbubble delivery to cardiac angiogenesis
    American Heart Association National Center
    to optimize the efficiency of microbubble targeted transfer of bioactive molecules to the heart, and to use this technique to investigate cardiac angiogenesis.