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TZID:Pacific/Honolulu
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CLASS:PUBLIC
CREATED:20260417T154310Z
DESCRIPTION:"Why Does the Yellow Fever\nLive-Attenuated 17D Vaccine Work?" by Alan Barrett, Ph.D., Director, Sealy Center for Vaccine Development, Professor, Department of Pathology and Department of Microbiology & Immunology, University of Texas Medical Branch, Galveston, Texas\n\nThe yellow fever 17D vaccine was developed in the 1930s and has been a very effective and safe vaccine with over 600 million doses distributed. Although the vaccine has been in use for nearly 80 years we still do not understand the mechanism(s) of attenuation or immunogencity. We have been using next generation sequencing to investigate 17D vaccine and evidence will be presented that attenuation is at least in part due to lack of quasispecies population on the vaccine virus. \n\n\n\nThe yellow fever 17D vaccine was developed in the 1930s and has been a very effective and safe vaccine with over 600 million doses distributed. Although the vaccine has been in use for nearly 80 years we still do not understand the mechanism(s) of attenuation or immunogencity. We have been using next generation sequencing to investigate 17D vaccine and evidence will be presented that attenuation is at least in part due to lack of quasispecies population on the vaccine virus.\n
DTEND;TZID=Pacific/Honolulu:20160523T230000Z
DTSTAMP:20260417T154310Z
DTSTART;TZID=Pacific/Honolulu:20160523T220000Z
LAST-MODIFIED:20260417T154310Z
LOCATION:John A. Burns School of Medicine, Kaka’ako Campus, 651 Ilalo Street, MEB Auditorium (Room 315)
PRIORITY:5
SEQUENCE:0
SUMMARY;LANGUAGE=en-us:COBRE/Tropical Medicine Seminar
TRANSP:OPAQUE
UID:177647659028935web-support-l@lists.hawaii.edu
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