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shohet and talliquist present trainees
Ralph Shohet and Michelle Taliquist present CCR’s trainees.

Training the next generation of cardiovascular researchers will continue at the University of Hawaiʻi at Mānoa John A. Burns School of Medicine (JABSOM), with a training grant renewal from the National Institutes of Health. The grant, which provides $385,000 annually for the next five years, will support postdoctoral fellows and graduate students studying cardiovascular science in JABSOM’s Center for Cardiovascular Research (CCR).

CCR aims to train scientists in cutting-edge technologies to advance cardiac biology and disease understanding. Research at the center focuses on heart damage, healing after infarction, and the cardiovascular effects of diseases like atherosclerosis, diabetes and obesity. The program also addresses diseases relevant toHawaiʻi, such as methamphetamine cardiomyopathy and Kawasaki Disease.

Cardiovascular disease remains the leading cause of death in Hawaiʻi, making this research vital for the state’s health. The grant not only advances scientific understanding but also supports economic development by creating jobs and fostering research in Hawaiʻi.

Success stories, mentoring focus

Over the past decade, the grant has supported 28 researchers, many of whom secured independent funding during their training.

“We’re proud to report that about half of our trainees have obtained funding while they’re still on the (grant), which then reopens slots for new trainees,” said Michelle Tallquist, director of this cycle.

jonathan yap and william boisvert in the lab
Jonathan Yap and his mentor, William Boisvert

Jonathan Yap, a quadriplegic Native Hawaiian researcher, is one of the grant’s success stories. Starting as an intern, Yap received an NIH grant, enabling him to become an independent investigator and establish his own lab.

“Dr. Yap has overcome the most devastating kinds of limitations you can imagine. He is a great example of the value of the (grant),” said Ralph Shohet, CCR director.

As the new funding cycle begins, CCR leaders are committed to mentoring and outreach. “We have recognized that an essential component of having a great training experience is strengthening our mentoring, so we’ve built this component into this next round,” said Tallquist.

The renewed grant will also focus on “mentoring the mentor,” ensuring that early-career scientists receive the guidance needed to become the next generation of mentors.

Read more at JABSOM.

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