"LASER ART" Special Seminar

March 2, 9:00am - 10:00am
Mānoa Campus, JABSOM, Kakaako Campus, 651 Ilalo Street, Medical Education Building Auditorium (Room 315) Add to Calendar

COBRE/Department of Tropical Medicine, Medical Microbiology & Pharmacology/Neuroscience & M.R. Research Program Joint Seminar: "LASER ART" by Dr. Howard E. Gendelman (Margaret R. Larson Professor of Infectious Diseases and Internal Medicine, Professor and Chair, Department of Pharmacology & Experimental Neuroscience, Editor-in-Chief, the Journal of Neuroimmune Pharmacology, University of Nebraska Medical Center).

Abstract: Advances in the development of long acting antiretroviral therapy (ART) can revolutionize current treatments for HIV/AIDS. We have coined the term long active slow effective release ART (LASER ART) based on properties of slow drug dissolution, poor water-solubility, excellent bioavailability, limited off target systemic toxicities, and excellent patient treatment adherence. Drug carrier technologies characterized by high payload of antiretroviral drugs (ARVs) in a single carrier are being developed to improve the pharmacokinetics and pharmacodynamics of the nanoformulated ART (nanoART). Additionally, surface modification of slow release antiretroviral carriers with targeting ligands has facilitated receptor-mediated transport across physiological barriers serves to improve therapeutic outcomes. The lecture will discuss the future of ART where LASER ART


Event Sponsor
Pacific Center for Emerging Infectious Diseases Research, TMMMP, Neuroscience & M.R. Research Program, Mānoa Campus

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(808) 692-1654

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