Caffeine & Epigenetics:Novel Approaches to Prevent and Treat UV- Induced Cance

May 21, 12:00pm - 1:00pm
Mānoa Campus, UH Cancer Center, Sullivan Conference Center

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Skin cancer is the most prevalent cancer in the United States and is strongly associated with ultraviolet (UV) radiation that damages DNA and generated many mutations. It is critical to avoid excessive sunlight in order to prevent skin cancer. Also, chemoprevention id of great interest. Human epidemiological studies and our mouse studies showed that caffeine prevents UV-induced skin carcinogenesis. We found that the most relevant target of caffeine for skin cancer prevention is the ATR kinase, which senses UV-induced DNA Lesions and stops the cell cycle. Genetic inhibition of ATR augmented UV-induced apoptosis and suppressed UV-induced skin cancer development.

Ticket Information
https://uhcancercenter.zoom.us/j/89403851035?pwd=q5xdbkKm6hnuOWWCzHLYyD2LJrVeq2.1 Password:153852

Event Sponsor
Mānoa Campus

More Information
Micehlle Yang, myang@cc.hawaii.edu, https://uhcancercenter.zoom.us/j/82780771071?pwd=cELB6WGDReGzb4y4u81OxBVG9EUbe

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Wednesday, May 21
11:30am	Join us for our May PIER Speaker Session | Strategies for Employers Mānoa Campus, 1410 Lower Campus Rd 171f, Honolulu, HI 96822
12:00pm	Caffeine & Epigenetics:Novel Approaches to Prevent and Treat UV- Induced Cance Mānoa Campus, UH Cancer Center, Sullivan Conference Center